Tango Therapeutics

Tango is a team of passionate problem solvers. Our discovery efforts begin and end with patients. We are driven by urgency and compassion, empowered by collaboration, courage and a culture of excellence – determined to push boundaries with innovative science and bold decisions. Together, we will discover transformative drugs for people with cancer by leveraging the classic principles of synthetic lethality in innovative ways. Our approaches are uncovering novel vulnerabilities in cancers with specific tumor suppressor gene loss and undruggable oncogenes, as well as discovering drug targets that reverse the ability of cancer cells to avoid immune destruction. We’re a team. And we’re all in for exciting science and changing lives. If you share our passion for discovering transformative cancer medicines and our deep commitment to making a difference for people with cancer and their families, please explore our current opportunities. Tango Therapeutics operates a biotechnology company created to discover novel drug targets and deliver the next generation of targeted therapies to people with cancer. The company's research leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at driver genes in cancer that are focused on three core areas, including counteracting tumor suppressor gene loss, reversing the ability of cancer cells to evade the immune system and identifying novel combinations, enabling patients to get therapies that are more effective than single-agent therapy.